Nerium SkinCare believes in the value of real relationships and is dedicated to offering skincare solutions that are based on proven science and actual customer success. We strongly believe in sustainable, honest, and informative practices, and consumer education. Therefore, Nerium SkinCare™ is constantly seeking new ways for our customers to participate in our research and educate themselves about their skin condition and our product ingredients.
Overview ST&T Research
Research for product safety and clinical application is provided for by ST&T Research (Science, Toxicology & Technology). ST&T Research is comprised of a group of prominent scientist, including M.D. and Ph.D. pharmacologists/toxicologist and research product development oriented physicians, scientist, and regulatory compliance specialists which include a legal team specializing in US FDA/FTC/Customs regulations. ST&T Research provides product development, product compliance, regulatory compliance, clinical testing, and information and data for safety and efficacy. Dr. Robert A. Newman who serves as a scientific advisor to Nerium SkinCare assisted by providing safety data from previous studies, experience from a FDA trial at the University of Texas M. D. Anderson Cancer Center, and the analytical analysis for the determination of oleandrin (CG) in blood plasma.
ST&T Research initiated human studies on various skin disorders (1. age/liver spots, actinic keratosis (2. acne vulgaris (3. sunburn (4. fever blisters / cold sores. The Nerium test article application was first applied as a spot treatment, then larger areas of skin application with each new clinical study. Two (2) of these clinical studies (acne, sunburn) included comparison to well-known OTC products currently available to consumers.
Each study's primary end-point was to evaluate the Nerium test articles for safety/toxicity, a) Determine if the Nerium oleander CG metabolites were being absorbed through the skin, b) If so, how much, c) If there was any noticeable blood pressure or heart rate changes, and d) If there were changes in blood chemistry or organ system functions. In addition, subjects were observed for inflammation, rash, or tenderness possibly related to the cream application.
ST&T utilized blood chemistry and CBC analysis whereby a comparison was made of the participant's baseline results with measurements taken throughout the study. As an example, participant blood samples were taken on day one (1) (one hour after cream application), day seven (7), day fifteen (15), and on day thirty (30) of product use to test for oleandrin (CG) absorption and accumulation in the blood.
Analysis was non-eventful. The blood analysis showed all subjects within normal ranges, there were no detectable CG's in the blood and no adverse reactions noted. The cardiac glycosides contained in Nerium oleander extracts were NOT ABLE to penetrate the skin at detectable levels in the blood. With regard to efficacy, ST&T was surprised to find there were a statistically significant number of subjects reporting positive results since the Nerium SkinCare test article contained no "additives" like the OTC products.