The following reports represent results of testing of Nerium Skincare products and their major components by an independent laboratory. Samples were sent to Mat-Tek, Inc. in a blinded fashion without the test facility knowing the identity of the samples supplied to them. The following is a summary of the test results. The test company uses a unique 3D model of human skin which is grown in tissue culture. Using the Mat-Tek system samples can be applied topically to human skin samples and changes monitored using both biochemical tests and histopathologic analyses using microscope examination of the tissue samples.

Nerium SkinCare does not use animal testing for any of its efficacy or safety tests.

Evaluation of a Nerium Formulation (NeriumFirm) on Oxidant and Skin Aging Endpoints in the EpiDerm FT in vitro Skin Model

Study Number:  047-14e

This study evaluated the effects of NeriumFirm on biomarkers of oxidation and skin-aging in a human skin model.  Accordingly, the study showed that NeriumFirm significantly increased expression of the gene for Metallothionein - 2A.  Metallothionein s are antioxidative proteins with the capacity to bind a wide array of heavy metals. The study showed that NeriumFirm increased the expression of genes encoding Metallothonein2A by at least two fold.

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